Today we're going to talk about clomiphene citrate or Clomid. A lot of doctors prescribe Clomid to their patients before they start TRT to see if they can help the body to make its own testosterone before injecting testosterone.
Today we're going to be talking about some medicines that many of you are familiar with. They are Clomid and Letrozole. I'm going to be talking about the mechanisms of actions of both of those, but first you should know that 40% of infertility is due to ovulation dysfunction, a disorder of ovulation. Many of those are polycystic ovarian syndrome patients.
These side effects are going to be secondary to estrogenic effects. Remember, it's an estrogen modulating agent. It's going to block at certain sites, and it's going to be pro stimulatory estrogenic throughout other parts of the body. This is true. As for men on TRT, I take care of myself, and we see that if you measure estradiol on Clomiphene, then it goes up.
Clomiphene is a very old-fashioned infertility medicine that's been around for many decades and is used mainly for women. It's been used classically in the recreational and professional anabolic steroid bodybuilding world for PCT. It's also used for male infertility, associated with anabolic steroid induced hypogonadism. And, of course, it's used as a sole agent for TRT.
The main focus that I hope to have in my practice is on male fertility and sexual dysfunction. So, two very different areas, occasionally they do overlap. For men with male fertility usually there are no signs and symptoms, except that he and his partner have been trying to have a child for a while, usually about a year or more, and when they're unable to achieve their goal of conception, and they usually get in contact with me for the male partner, as the woman is also undergoing an evaluation with her doctor.
If you are trying to conceive, the fertility medication, known as Clomiphene Citrate or Clomid, may be an option for you. Clomid is used in two circumstances. First, Clomid is used for women, who don't ovulate, to try to induce ovulation. The Clomid is also used for women, who already ovulate, to try to further improve their chances for getting pregnant.
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